Data from: Decreased brain connectivity in smoking contrasts with increased connectivity in drinking

Wei Cheng, Edmund T. Rolls, Trevor W. Robbins, Weikang Gong, Zhaowen Liu, Wujun Lv, Jingnan Du, Hongkai Wen, Liang Ma, Erin Burke Quinlan, Hugh Garavan, Eric Artiges, Dimitri Papadopoulos Orfanos, Michael N. Smolka, Gunter Schumann, Keith Kendrick & Jianfeng Feng
In a group of 831 participants from the general population in the Human Connectome Project, smokers exhibited low overall functional connectivity, and more specifically of the lateral orbitofrontal cortex which is associated with non-reward mechanisms, the adjacent inferior frontal gyrus, and the precuneus. Participants who drank a high amount had overall increases in resting state functional connectivity, and specific increases in reward-related systems including the medial orbitofrontal cortex and the cingulate cortex. Increased impulsivity was...
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