Data from: 18F-fluorodeoxyglucose positron-emission tomography (FDG-PET)-Radiomics of metastatic lymph nodes and primary tumor in non-small cell lung cancer (NSCLC) – A prospective externally validated study

Sara Carvalho, Ralph T. H. Leijienaar, Esther G. C. Troost, Janna E. Van Timmeren, Cary Oberije, Wouter Van Elmpt, Lioe-Fee De Geus-Oei, Johan Bussink, Philippe Lambin & Ralph T. H. Leijenaar
Background: Lymph node stage prior to treatment is strongly related to disease progression and poor prognosis in non-small cell lung cancer (NSCLC). However, few studies have investigated metabolic imaging features derived from pre-radiotherapy 18F-fluorodeoxyglucose (FDG) positron-emission tomography (PET) of metastatic hilar/mediastinal lymph nodes (LNs). We hypothesized that these would provide complementary prognostic information to FDG-PET descriptors to only the primary tumor (tumor). Methods: Two independent cohorts of 262 and 50 node-positive NSCLC patients were used...
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