Data from: Molecular evolution of the proopiomelanocortin system in Barn owl species

Karin Löw, Anne-Lyse Ducrest, Luis San-Jose, Céline Simon, Vera Uva, Nabil Seidah, Antonella Pasquato, Stefan Kunz & Alexandre Roulin
Examination of genetic polymorphisms in outbred wild-living species provides insights into the evolution of complex systems. In higher vertebrates, the proopiomelanocortin (POMC) precursor gives rise to α-, β-, and γ-melanocyte-stimulating hormones (MSH), which are involved in numerous physiological aspects. Genetic defects in POMC are linked to metabolic disorders in humans and animals. In the present study, we undertook an evolutionary genetics approach complemented with biochemistry to investigate the functional consequences of genetic polymorphisms in the...
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