Data from: Evolution of functional antibodies following acute Epstein-Barr Virus infection

Christina Karsten, Yannic Bartsch, Sally Shin, Matthew Slein, Howard Heller, Kumaran Kolandaivelu, Jaap Middeldorp, Galit Alter & Boris Julg
While Epstein-Barr virus causes mostly asymptomatic infection, associated malignancies, and autoimmune and lymphoproliferative diseases occur. To dissect the evolution of humoral immune responses over the course of EBV infection and to gain a better understanding of the potential contribution of antibody (Ab) function to viral control, we comprehensively profiled Ab specificities and Fc-functionalities using systems serology and VirScan. Ab functions against two early (p18 and p47/54) and two latent (gp350/220 and EBNA-1) EBV proteins were...
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