Data from: Upregulation of NLRP3 inflammasome in the tears and ocular surface of dry eye patients

Liangliang Niu, Shujie Zhang, Jihong Wu, Ling Chen & Yan Wang
Purpose: To evaluate the mRNA and protein expressions of NLRP3 inflammasome and its downstream inflammatory factors in human dry eye. Methods: We recruited 54 patients with Sjögren’s syndrome dry eye (SSDE), 50 patients with non-Sjögren’s syndrome dry eye (NSSDE), and 46 healthy controls. Tear film breakup time (TBUT), Schirmer I test, and fluorescein staining (FL) were performed on all subjects. Tear samples were obtained to analyze the inflammatory cytokine levels of IL-1β and IL-18 via...
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