Data from: Evaluating the reliability of microsatellite genotyping from low-quality DNA templates with a polynomial distribution model

Gang He, Kang Huang, SongTao Guo, WeiHong Ji, Yi Ren, XueLin Jin & BaoGuo Li
Molecular studies using trace DNA, such as from museum specimens, ancient or forensic samples and samples obtained noninvasively, often have a common problem of low quality of DNA templates. Amplification errors, such as allelic dropout and false allele, may arise during polymerase chain reaction (PCR) using such samples. A mathematical model which treats homozygotes and heterozygotes discriminately has been developed to measure sample quality and compute the confidence level of using multiple-tube approaches. We use...
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