Data from: The fitness of drug-resistant malaria parasites in a rodent model: multiplicity of infection

Silvie Huijben, Derek G. Sim, William A. Nelson & Andrew F. Read
Malaria infections normally consist of more than one clonally-replicating lineage. Within-host interactions between sensitive and resistant parasites can have profound effects on the evolution of drug resistance. Here, using the Plasmodium chabaudi mouse malaria model, we ask whether the costs and benefits of resistance are affected by the number of co-infecting strains competing with a resistant clone. We found strong competitive suppression of resistant parasites in untreated infections and marked competitive release following treatment. The...
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