Detecting selection using extended haplotype homozygosity (EHH)-based statistics in unphased or unpolarized dataAlexander Klassmann & Mathieu Gautier
Analysis of population genetic data often includes the search for genomic regions with signs of recent positive selection. One of the approaches involves the concept of Extended Haplotype Homozygosity (EHH) and its associated statistics. These statistics typically need phased haplotypes and, some of them, polarized variants. Here, we unify and extend previously proposed modifications to loosen these requirements. We compare the modified versions with the original ones by measuring the False Discovery Rate in simulated...
1 citation reported since publication in 2020.
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