Data from: Drug repurposing: a systematic approach to evaluate candidate oral neuroprotective interventions for secondary progressive multiple sclerosis

Hanna M. Vesterinen, Peter Connick, Cadi M. J. Irvine, Emily S. Sena, Kieren J. Egan, Gary G. Carmichael, Afiyah Tariq, Sue Pavitt, Jeremy Chattaway, Malcolm Robert Macleod, Siddharthan Chandran & Jeremy Chataway
Objective: To develop and implement an evidence based framework to select, from drugs already licenced, candidate oral neuroprotective drugs to be tested in secondary progressive multiple sclerosis. Design: Systematic review of clinical studies of oral putative neuroprotective therapies in MS and four other neurodegenerative diseases with shared pathological features, followed by systematic review and meta-analyses of the in vivo experimental data for those interventions. We presented summary data to an international multi-disciplinary committee, which assessed...
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