Data from: A mechanistic underpinning for sigmoid dose-dependent infection

Jani Anttila, Lauri Mikonranta, Tarmo Ketola, Veijo Kaitala, Jouni Laakso & Lasse Ruokolainen
Theoretical models of environmentally transmitted diseases often assume that transmission is a constant process, which scales linearly with pathogen dose. Here we question the applicability of such an assumption and propose a sigmoidal form for the pathogens infectivity response. In our formulation, this response arises under two assumptions: 1) multiple invasion events are required for a successful pathogen infection and 2) the host invasion state is reversible. The first assumption reduces pathogen infection rates at...
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