Data from: A simple genetic basis of adaptation to a novel thermal environment results in complex metabolic rewiring in Drosophila

François Mallard, Viola Nolte, Ray Tobler, Martin Kapun & Christian Schlötterer
Background: Population genetic theory predicts that rapid adaptation is largely driven by complex traits encoded by many loci of small effect. Because large-effect loci are quickly fixed in natural populations, they should not contribute much to rapid adaptation. Results: To investigate the genetic architecture of thermal adaptation — a highly complex trait — we performed experimental evolution on a natural Drosophila simulans population. Transcriptome and respiration measurements reveal extensive metabolic rewiring after only approximately 60...
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