Data from: Adhesion forces and mechanics in mannose-mediated acanthamoeba interactions

Steven Huth, Julia F. Reverey, Matthias Leippe & Christine Selhuber‐Unkel
The human pathogenic amoeba Acanthamoeba castellanii (A. castellanii) causes severe diseases, including acanthamoeba keratitis and encephalitis. Pathogenicity arises from the killing of target-cells by an extracellular killing mechanism, where the crucial first step is the formation of a close contact between A. castellanii and the target-cell. This process is mediated by the glycocalix of the target-cell and mannose has been identified as key mediator. The aim of the present study was to carry out a...
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