Pupil and masking responses to light as functional measures of retinal degeneration in mice Mus Musculus

Stewart Thompson, Ethan Contreras, Carley Dearing, Crystal Ashinhurst, Betty Fish, Sajila Hossain, Ariana Rey & Primal Silva
Background: Pre-clinical testing of retinal pathology and treatment efficacy depends on reliable and valid measures of retinal function. The electroretinogram (ERG) and tests of visual acuity are the ideal standard, but can be unmeasurable while useful vision remains. Non-image-forming responses to light such as the pupillary light reflex (PLR) are attractive surrogates. However, it is not clear how accurately such responses reflect changes in visual capability in specific disease models. The purpose of this study...
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These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?