Effects of cold or warm ischemia and ex-vivo lung perfusion on the release of damage associated molecular patterns and inflammatory cytokines in experimental lung transplantation

Roumen Parapanov, Arpad Hasenauer, Benoit Bedat, Jérôme Lugrin, Anne Debonneville, Etienne Abdelnour, Michel Gonzalez, Jean Perentes, Lise Piquilloud, Csaba Szabo, Thorsten Krueger & Lucas Liaudet
Lung transplantation (LTx) is associated with sterile inflammation, possibly related to the release of damage associated molecular patterns (DAMPs) by injured allograft cells. We have measured cellular damage and the release of DAMPs and cytokines in an experimental model of LTx after cold or warm ischemia and examined the effect of pretreatment with ex-vivo lung perfusion (EVLP).
1 citation reported since publication in 2021.
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