Data from: Is there a causal link between knee loading and knee osteoarthritis progression? A systematic review and meta-analysis of cohort studies and randomised trials
Marius Henriksen, Mark W. Creaby, Hans Lund, Carsten Juhl & Robin Christensen
Objective: We performed a systematic review, meta-analysis and assessed the evidence supporting a causal link between knee joint loading during walking and structural knee osteoarthritis (OA) progression. Design: Systematic review, meta-analysis and application of Bradford Hill's considerations on causation. Data sources: We searched MEDLINE, Scopus, AMED, CINAHL and SportsDiscus for prospective cohort studies and randomised controlled trials (RCTs) from 1950 through October 2013. Study eligibility criteria: We selected cohort studies and RCTs in which estimates...
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