Data from: Anthrax toxin receptor 1 is essential for arteriogenesis in a mouse model of hindlimb ischemia

Nicholas J. Andersen, Elissa A. Boguslawski, Agni S. Naidu, Christopher Szot, Jennifer L. Bromberg-White, Kara Kits, Cynthia Y. Kuk, Laura E. Holton, Bradley St. Croix, Christopher M. Chambers & Nicholas S. Duesbery
Anthrax toxin receptor 1/tumor endothelial marker 8 (Antxr1 or TEM8) is up-regulated in tumor vasculature and serves as a receptor for anthrax toxin, but its physiologic function is unclear. The objective of this study was to evaluate the role of Antxr1 in arteriogenesis. The role of Antxr1 in arteriogenesis was tested by measuring gene expression and immunohistochemistry in a mouse model of hindlimb ischemia using wild-type and ANTXR1-/- mice. Additional tests were performed by measuring...
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