Data from: Rab6 is required for multiple apical transport pathways but not the basolateral transport pathway in Drosophila photoreceptors

Nozomi Iwanami, Yuri Nakamura, Takunori Satoh, Ziguang Liu & Akiko K. Satoh
Polarized membrane trafficking is essential for the construction and maintenance of multiple plasma membrane domains of cells. Highly polarized Drosophila photoreceptors are an excellent model for studying polarized transport. A single cross-section of Drosophila retina contains many photoreceptors with 3 clearly differentiated plasma membrane domains: a rhabdomere, stalk, and basolateral membrane. Genome-wide high-throughput ethyl methanesulfonate screening followed by precise immunohistochemical analysis identified a mutant with a rare phenotype characterized by a loss of 2 apical...
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