Age-specific activation patterns and inter-subject similarity during verbal working-memory maintenance and Cognitive Reserve

Christian Habeck, Yunglin Gazes & Yaakov Stern
Cognitive Reserve, according to a recent consensus definition of the NIH-funded Reserve and Resilience collaboratory (https://reserveandresilience.com/), is constituted by any mechanism contributing to cognitive performance beyond, or interacting with, brain structure in the widest sense. To identity multivariate activation patterns fulfilling this postulate, we investigated a verbal Sternberg fMRI task and imaged 181 people with age coverage in the ranges 20-30 (44 participants) and 55-70 (137 participants). Beyond task performance, participants were characterized in terms...
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