Protein structure alignments and structural similarity score code for: Benchmarking methods of protein structure alignment

Janan Sykes
The function of a protein is primarily determined by its structure and amino acid sequence. Many biological questions of interest rely on being able to accurately determine the group of structures to which domains of a protein belong (often referred to as their `fold'); this can be done through alignment and comparison of protein structures. This fundamental task underpins predicting function, identification of homology, and testing hypotheses about the way "protein-space'' is organised. Dozens of...
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