Data from: The impact of pathological high-frequency oscillations on hippocampal network activity in rats with chronic epilepsy

Laura A. Ewell, Kyle B. Fischer, Christian Leibold, Stefan Leutgeb & Jill K. Leutgeb
In epilepsy, brain networks generate pathological high-frequency oscillations (pHFOs) during interictal periods. To understand how pHFOs differ from normal oscillations in overlapping frequency bands and potentially perturb hippocampal processing, we performed high-density single unit and local field potential recordings from hippocampi of behaving rats with and without chronic epilepsy. In epileptic animals, we observed two types of co-occurring fast oscillations, which by comparison to control animals we could classify as ‘ripple-like’ or ‘pHFO’. We compared...
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