β-Elemene derivatives produced from SeO2-mediated oxidation reaction

Xingrui He, Xiao-Tao Zhuo, Yuan Gao, Renren Bai, Xiang-Yang Ye & Tian Xie
We report herein the first access of ß-elemene derivatives through the SeO2-mediated oxidation reaction. Several new compounds were isolated through such one-step reaction, and their structures were elucidated using various 2D-NMR techniques. This method provides easy access to multiple oxidative ß-elemene derivatives in one single step, and represents the first cyclohexyl ring modifications of ß-elemene. It’s expected to open up the opportunity for future derivatization on cyclohexyl ring of ß-elemene. The new compounds obtained above...
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