A single locus regulates a female-limited color pattern polymorphism in a reptile

Nathalie Feiner
Animal coloration is often expressed in periodic patterns that can arise from differential cell migration, yet how these processes are regulated remains elusive. We show that a female-limited polymorphism in dorsal patterning (diamond/chevron) in the brown anole is controlled by a single Mendelian locus. This locus contains the gene CCDC170 that is adjacent to, and co-expressed with, the Estrogen receptor-1 gene, explaining why the polymorphism is female-limited. CCDC170 is an organizer of the Golgi-microtubule network...
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