Data from: Perturbing the cellular cevels of steroid receptor coactivator-2 impairs murine endometrial function

Maria M. Szwarc, Ramakrishna Kommagani, Jae-Wook Jeong, San-Pin Wu, Sophia Y. Tsai, Ming-Jer Tsai, Bert W. O'Malley, Francesco J. DeMayo & John P. Lydon
As pleiotropic coregulators, members of the p160/steroid receptor coactivator (SRC) family control a broad spectrum of transcriptional responses that underpin a diverse array of physiological and pathophysiological processes. Because of their potent coregulator properties, strict controls on SRC expression levels are required to maintain normal tissue functionality. Accordingly, an unwarranted increase in the cellular levels of SRC members has been causally linked to the initiation and/or progression of a number of clinical disorders. Although knockout...
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