Data from: MHC structuring and divergent allele advantage in a urodele amphibian: a hierarchical multi-scale approach

Lorenzo Talarico, Wieslaw Babik, Silvio Marta, Venusta Pietrocini & Marco Mattoccia
The proteins encoded by extraordinarily polymorphic major histocompatibility complex (MHC) genes are involved in the adaptive immune response. Balancing selection is believed to maintain MHC polymorphism in the long-term, although neutral processes also play a role in shaping MHC diversity. However, the relative contribution of these processes is poorly understood. Here we characterized MHC class II variation of a low-dispersal, pond-breeding newt (Triturus carnifex) over a restricted, geographically structured area. We aimed to: (1) evaluate...
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