Data from: Using Drosophila melanogaster to identify chemotherapy toxicity genes

Elizabeth G. King, Galina Kislukhin, Kelli N. Walters & Anthony D. Long
The severity of the toxic side effects of chemotherapy shows a great deal of interindividual variability, and much of this variation is likely genetically based. Simple DNA tests predictive of toxic side effects could revolutionize the way chemotherapy is carried out. Due to the challenges in identifying polymorphisms that affect toxicity in humans, we use Drosophila fecundity following oral exposure to carboplatin, gemcitabine and mitomycin C as a model system to identify naturally occurring DNA...
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