Data from: Resistance gene carriage predicts growth of natural and clinical Escherichia coli isolates in the absence of antibiotics

Richard C. Allen, Daniel C. Angst & Alex R. Hall
Bacterial pathogens that carry antibiotic resistance alleles sometimes pay a cost in the form of impaired growth in antibiotic-free conditions. This cost of resistance is expected to be a key parameter for understanding how resistance spreads and persists in pathogen populations. Analysis of individual resistance alleles from laboratory evolution and natural isolates has shown they are typically costly, but these costs are highly variable and influenced by genetic variation at other loci. It therefore remains...
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