Data from: Whole genome sequencing shows sleeping sickness relapse is due to parasite regrowth and not reinfection

Joshua Richardson, Benjamin Evans, Patient P. Pyana, Nick Van Reet, Mark Sistrom, Philippe Buscher, Serap Aksoy, Aldalgisa Caccone, Joshua B. Richardson & Adalgisa Caccone
The trypanosome Trypanosoma brucei gambiense (Tbg) is a cause of human African trypanosomiasis (HAT) endemic to many parts of sub-Saharan Africa. The disease is almost invariably fatal if untreated and there is no vaccine, which makes monitoring and managing drug resistance highly relevant. A recent study of HAT cases from the Democratic Republic of the Congo reported a high incidence of relapses in patients treated with melarsoprol. Of the 19 Tbg strains isolated from patients...
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