Data from: Genetic switches designed for eukaryotic cells and controlled by serine integrases

Mayna Gomide, Thais Sales, Luciana Barros, Cintia Limia, Marco Antônio Oliveira, Lilian Florentino, Leila Barros, Maria Laura Robledo, Gustavo José, Mariana Almeida, Rayane Lima, Stevens Rehen, Cristiano Lacorte, Eduardo Melo, André Murad, Martín Bonamino, Cintia Coelho & Elibio Rech
Recently, new serine integrases have been identified, increasing the possibility of scaling up genomic modulation tools. Here, we describe the use of unidirectional genetic switches to evaluate the functionality of six serine integrases in different eukaryotic systems: the HEK 293T cell lineage, bovine fibroblasts and plant protoplasts. Moreover, integrase activity was also tested in human cell types of therapeutic interest: peripheral blood mononuclear cells (PBMCs), neural stem cells (NSCs) and undifferentiated embryonic stem (ES) cells....
1 citation reported since publication in 2019.
74 views reported since publication in 2019.

These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?
5 downloads reported since publication in 2019.

These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?