Data from: Evolution of mutation rates in hypermutable populations of Escherichia coli propagated at very small effective population size

Tanya Singh, Meredith Hyun & Paul Sniegowski
Mutation is the ultimate source of the genetic variation—including variation for mutation rate itself—that fuels evolution. Natural selection can raise or lower the genomic mutation rate of a population by changing the frequencies of mutation rate modifier alleles associated with beneficial and deleterious mutations. Existing theory and observations suggest that where selection is minimized, rapid systematic evolution of mutation rate either up or down is unlikely. Here, we report systematic evolution of higher and lower...
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