SNP genotypes for healthy and CIM-affected GSDs

Leigh Anne Clark, Sarah Bell, Jacquelyn Evans, Katy Evans, Kate Tsai, Rooksana Noorai, Thomas Famula & Dolores Holle
German shepherd dogs (GSDs) are predisposed to an inherited motility disorder of the esophagus, termed congenital idiopathic megaesophagus (CIM), in which swallowing is ineffective and the esophagus is enlarged. Affected puppies are unable to properly pass food into their stomachs and consequently regurgitate their meals and show a failure to thrive, often leading to euthanasia. Here, we generated genome-wide SNP profiles for healthy and CIM-affected GSDs using the Illumina CanineHD BeadChip, containing 220,853 SNPs.
1 citation reported since publication in 2021.
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