Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment

Julie Lang, Anna Capasso, Kimberly R. Jordan, Jena D. French, Adwitiya Kar, Stacey M. Bagby, Jacob Barbee, Betelehem W. Yacob, Lia S. Head, Kenneth D. Tompkins, Brian M. Freed, Hilary Somerset, Toshimasa J. Clark, Todd M. Pitts, Well A. Messersmith, S. Gail Eckhardt, Margaret E. Wierman, Stephen Leong & Katja Kiseljak-Vassiliades
Context: While the development of immune checkpoint inhibitors has transformed treatment strategies of several human malignancies, research models to study immunotherapy in ACC are lacking. Objective: To explore the effect of anti-PD1 immunotherapy on the alteration of the immune milieu in ACC in a newly generated preclinical model and correlate with the response of the matched patient. Design, Setting and Intervention: To characterize the CU-ACC2-M2B patient-derived xenograft in a humanized mouse model, evaluate the effect...
1 citation reported since publication in 2019.
70 views reported since publication in 2019.

These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?
4 downloads reported since publication in 2019.

These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?