Data from: Evolution of antigenic diversity in the tick-transmitted bacterium Borrelia afzelii: a role for host specialization?

Lars Råberg, Åsa Hagström, Martin Andersson, Simona Bartkova, Kristin Scherman, Maria Strandh & Barbara Tschirren
Antigenic diversity in pathogenic microbes can be a result of at least three different processes: diversifying selection by acquired immunity, host-pathogen coevolution, and/or host specialization. Here, we investigate if host specialization drives diversity at ospC (which encodes an immunodominant surface protein) in the tick-transmitted bacterium Borrelia afzelii. We determined prevalence and infection intensity of ospC strains in naturally infected wild mammals (rodents and shrews) by 454 amplicon sequencing in combination with qPCR. Neither prevalence nor...
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