Data from: Relevance of heterokaryosis for adaptation and azole-resistance development in Aspergillus fumigatus

Jianhua Zhang, Eveline E. Snelders, Bas J. Zwaan, Sijmen E. Schoustra, Ed J. Kuijper, Maiken C. Arendrup, Willem J.G. Melchers, Paul E. Verweij, Alfons J.M. Debets & Alfons J. M. Debets
Aspergillus fumigatus causes a range of diseases in humans, some of which are characterized by fungal persistence. A. fumigatus, being a generalist saprotroph, may initially establish lung colonisation due to its physiological versatility and subsequently adapt through genetic changes to the human lung environment and antifungal treatments. Human lung-adapted genotypes can arise by spontaneous mutation and/or recombination and subsequent selection of the fittest genotypes. Sexual and asexual spores are considered crucial contributors to the genetic...
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