Spatiotemporal analyses reveal infectious disease-driven selection in a free-ranging ungulate

Melanie E.F. LaCava, Jennifer L. Malmberg, William H. Edwards, Laura N.L. Johnson, Samantha E. Allen & Holly B. Ernest
Infectious diseases play an important role in wildlife population dynamics by altering individual fitness, but detecting disease-driven natural selection in free-ranging populations is difficult due to complex disease-host relationships. Chronic wasting disease (CWD) is a fatal infectious prion disease in cervids for which mutations in a single gene have been mechanistically linked to disease outcomes, providing a rare opportunity to study disease-driven selection in wildlife. In Wyoming, USA, CWD has gradually spread across mule deer...
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