Data from: In-solution hybridization for mammalian mitogenome enrichment: pros, cons and challenges associated with multiplexing degraded DNA

Melissa T. R. Hawkins, Courtney A. Hofman, Taylor Callicrate, Molly M. McDonough, Mirian T. N. Tsuchiya, Eliécer E. Gutierrez, Kristofer M. Helgen & Jesús E. Maldonado
Here, we present a set of RNA-based probes for whole mitochondrial genome in-solution enrichment, targeting a diversity of mammalian mitogenomes. This probes set was designed from seven mammalian orders and tested to determine the utility for enriching degraded DNA. We generated 63 mitogenomes representing five orders and 22 genera of mammals that yielded varying coverage ranging from 0 to >5400X. Based on a threshold of 70% mitogenome recovery and at least 10× average coverage, 32...
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