Data from: Presynaptic GABAB receptors functionally uncouple somatostatin interneurons from the active hippocampal network

Sam A. Booker, Harumi Harada, Claudio Elguate, Julia Bank, Bartos Marlene, Akos Kulik & Imre Vida
Information processing in cortical neuronal networks relies on properly balanced excitatory and inhibitory neurotransmission. A ubiquitous motif for maintaining this balance is the somatostatin interneuron (SOM-IN) feedback microcircuit. Here, we investigate the modulation of this microcircuit by presynaptic GABAB receptors (GABABRs) in the rat hippocampus. Whole-cell recordings from SOM-INs reveal that both excitatory and inhibitory synaptic inputs are strongly inhibited by GABABRs, while optogenetic activation of the interneurons shows that their inhibitory output is also...
1 citation reported since publication in 2019.
67 views reported since publication in 2019.

These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?
13 downloads reported since publication in 2019.

These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?