Data from: Reporting tumor molecular heterogeneity in histopathological diagnosis

Andrea Mafficini, Eliana Amato, Matteo Fassan, Michele Simbolo, Davide Antonello, Caterina Vicentini, Maria Scardoni, Samantha Bersani, Marisa Gottardi, Borislav Rusev, Giorgio Malpeli, Vincenzo Corbo, Stefano Barbi, Katarzyna O. Sikora, Rita T. Lawlor, Giampaolo Tortora & Aldo Scarpa
Background: Detection of molecular tumor heterogeneity has become of paramount importance with the advent of targeted therapies. Analysis for detection should be comprehensive, timely and based on routinely available tumor samples. Aim: To evaluate the diagnostic potential of targeted multigene next-generation sequencing (TM-NGS) in characterizing gastrointestinal cancer molecular heterogeneity. Methods: 35 gastrointestinal tract tumors, five of each intestinal type gastric carcinomas, pancreatic ductal adenocarcinomas, pancreatic intraductal papillary mucinous neoplasms, ampulla of Vater carcinomas, hepatocellular carcinomas,...
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