Data from: Heterozygote advantage at MHC DRB may influence response to infectious disease epizootics

Amy J. Osborne, John Pearson, Sandra S. Negro, B. Louise Chilvers, Martin A. Kennedy & Neil J. Gemmell
The effect of MHC polymorphism on individual fitness variation in the wild remains equivocal; however, much evidence suggests that heterozygote advantage is a major determinant. To understand the contribution of MHC polymorphism to individual disease resistance or susceptibility in natural populations, we investigated two MHC class II B loci, DQB and DRB, in the New Zealand sea lion (NZSL, Phocarctos hookeri). The NZSL is a threatened species which is unusually susceptible to death by bacterial...
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