Reduced stress defense responses contribute to the higher toxicity of a pesticide under warming

Vienna Delnat, Janne Swaegers, Jana Asselman & Robby Stoks
There is a pressing need to identify the molecular mechanisms underlying the, often magnifying, interactive effects between contaminants and natural stressors. We here test our hypothesis that lower general stress defense responses contribute to synergistic interactions between stressors. We focus on the widespread pattern that many contaminants are more toxic at higher temperatures. Specifically, we tested the effects of an environmentally realistic low-effect and high-effect concentration of the pesticide chlorpyrifos under warming at the gene...
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