A chromosome-scale reference genome and genome-wide genetic variations elucidate adaptation in yak

Jin-Cheng Zhong, Qiu-Mei Ji, Jin-Wei Xin, Zhi-Xin Chai, Cheng-Fu Zhang, Yangla Dawa, Sang Luo, Qiang Zhang, Zhandui Pingcuo, Min-Sheng Peng, Yong Zhu, Han-Wen Cao, Hui Wang & Jian-Lin Han
Yak is an important livestock for the people who lived in harsh and oxygen-deprived Qinghai-Tibetan Plateau and Hindu-Kush Himalayan Mountains. Although there is a yak genome be sequenced in 2012, the assembly is quite fragmented due to the limitation of Illumina sequencing technology. An accurate and complete reference genome is critical for studying genetic variation of a specie. Long-read sequences are more complete than short-read ones, and they have been successfully used for high-quality genome...
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