Mutation of rpoB shifts the nutrient threshold triggering Myxococcus multicellular development

Sabrina A. Eisner, Gregory J. Velicer & Yuen-Tsu N. Yu
The ability to perceive and respond to environmental change is essential to all organisms. In response to nutrient depletion, cells of the soil-dwelling δ-proteobacterium Myxococcus xanthus undergo collective morphogenesis into multicellular fruiting bodies and transform into stress-resistant spores. This process is strictly regulated by gene networks that incorporate both inter- and intracellular signals. While commonly studied M. xanthus reference strains and some natural isolates undergo development only in nutrient-poor conditions, some lab mutants and other...
1 citation reported since publication in 2021.
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