Data from: Selective sweeps of mitochondrial DNA can drive the evolution of uniparental inheritance

Joshua R. Christie & Madeleine Beekman
While the uniparental (or maternal) inheritance of mitochondrial DNA (mtDNA) is widespread, the reasons for its evolution remain unclear. Two main hypotheses have been proposed: selection against individuals containing different mtDNAs (heteroplasmy) and selection against “selfish” mtDNA mutations. Recently, uniparental inheritance was shown to promote adaptive evolution in mtDNA, potentially providing a third hypothesis for its evolution. Here we explore this hypothesis theoretically and ask if the accumulation of beneficial mutations provides a sufficient fitness...
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