Data from: Population persistence under high mutation rate: from evolutionary rescue to lethal mutagenesis

Yoann Anciaux, Amaury Lambert, Ophelie Ronce, Lionel Roques & Guillaume Martin
Populations may genetically adapt to severe stress that would otherwise cause their extirpation. Recent theoretical work, combining stochastic demography with Fisher’s Geometric Model of adaptation, has shown how evolutionary rescue becomes unlikely beyond some critical intensity of stress. Increasing mutation rates may however allow adaptation to more intense stress, raising concerns about the effectiveness of treatments against pathogens. This previous work assumes that populations are rescued by the rise of a single resistance mutation. However,...
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