Data from: The impact of library preparation protocols on the accuracy of allele frequency estimates in Pool-Seq data

Robert Kofler, Viola Nolte & Christian Schlötterer
Sequencing pools of individuals (Pool-Seq) is a cost-effective method to determine genome-wide allele frequency estimates. Given the importance of meta-analyses combining data sets, we determined the influence of different genomic library preparation protocols on the consistency of allele frequency estimates. We found that typically no more than 1% of the variation in allele frequency estimates could be attributed to differences in library preparation. Also read length had only a minor effect on the consistency of...
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