Data from: High virulence sub-populations in Pseudomonas aeruginosa long-term cystic fibrosis airway infections

Siobhan O'Brien, David Williams, Joanne L. Fothergill, Steve Paterson, Winstanley Craig & Michael A. Brockhurst
Background: Pseudomonas aeruginosa typically displays loss of virulence-associated secretions over the course of chronic cystic fibrosis infections. This has led to the suggestion that virulence is a costly attribute in chronic infections. However, previous reports suggest that overproducing (OP) virulent pathotypes can coexist with non-producing mutants in the CF lung for many years. The consequences of such within-patient phenotypic diversity for the success of this pathogen are not fully understood. Here, we provide in-depth quantification...
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