Data from: Cardiomyocyte mechanodynamics under conditions of actin remodelling

Ricardo H. Pires, Nithya Shree, Emmanuel Manu, Ewa Guzniczak & Oliver Otto
The mechanical performance of cardiomyocytes is an important indicator of their maturation state and of primary importance for the development of therapies based on cardiac stem-cells. As the mechanical analysis of adherent cells at high-throughput remains challenging, we explore the applicability of real-time deformability cytometry (RT-DC) to probe cardiomyocytes in suspension. RT-DC is a microfluidic technology allowing for real-time mechanical analysis of thousands of cells with a throughput exceeding 1,000 cells per second. For cardiomyocytes...
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