Data from: Multicopy single-stranded DNA directs intestinal colonization of enteric pathogens

Johanna R. Elfenbein, Leigh A. Knodler, Ernesto S. Nakayasu, Charles Ansong, Heather M. Brewer, Lydia Bogomolnaya, L. Garry Adams, Michael McClelland, Joshua N. Adkins & Helene L. Andrews-Polymenis
Multicopy single-stranded DNAs (msDNAs) are hybrid RNA-DNA molecules encoded on retroelements called retrons and produced by the action of retron reverse transcriptases. Retrons are widespread in bacteria but the natural function of msDNA has remained elusive despite 30 years of study. The major roadblock to elucidation of the function of these unique molecules has been the lack of any identifiable phenotypes for mutants unable to make msDNA. We report that msDNA of the zoonotic pathogen...
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