Data from: Intestinal Ralstonia pickettii augments glucose intolerance in obesity

Shanthadevi Udayappan, Petia Kovatcheva-Datchary, Guido Bakker, Stefan Havik, Hilde Herrema, Patrice Cani, Kristien Bouter, Clara Belzer, Julia J. Witjes, Anne Vrieze, Eleonore Susanne Victoria De Sonnaville, Alice Chaplin, Daniel Van Raalte, Steven Aalvink, Geesje Dallinga-Thie, Hans Heilig, Goran Bergstrom, Suzan Van Der Meij, Bart Van Wagensveld, Joost Hoekstra, Frits Holleman, Erik Stroes, Albert Groen, Fredrik Backhed, Willem De Vos … & Daniel H. Van Raalte
An altered intestinal microbiota composition has been implicated in the pathogenesis of metabolic disease including obesity and type 2 diabetes mellitus (T2DM). Low grade inflammation, potentially initiated by the intestinal microbiota, has been suggested to be a driving force in the development of insulin resistance in obesity. Here, we report that bacterial DNA is present in mesenteric adipose tissue of obese but otherwise healthy human subjects. Pyrosequencing of bacterial 16S rRNA genes revealed that DNA...
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