Data from: Within-host competition and drug resistance in the human malaria parasite Plasmodium falciparum

Mary Bushman, Lindsay Morton, Nancy Duah, Neils Quashie, Benjamin Abuaku, Kwadwo Koram, Pedro Dimbu, Mateusz Plucinski, Julie Gutman, Peter Lyaruu, Steven Kachur, Jacobus De Roode, Venkatachalam Udhayakumar, Jacobus C. De Roode, S. Patrick Kachur & Kwadwo A. Koram
Infections with the malaria parasite Plasmodium falciparum typically comprise multiple strains, especially in high-transmission areas where infectious mosquito bites occur frequently. However, little is known about the dynamics of mixed-strain infections, particularly whether strains sharing a host compete or grow independently. Competition between drug-sensitive and drug-resistant strains, if it occurs, could be a crucial determinant of the spread of resistance. We analyzed 1,341 P. falciparum infections in children from Angola, Ghana, and Tanzania and found...
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