Corticothalamic gating of population auditory thalamocortical transmission in mouse

Baher Ibrahim, Caitlin Murphy, Georgiy Yudintsev, Matthew I. Banks, Daniel A. Llano & Yoshitaka Shinagawa
The mechanisms that govern thalamocortical transmission are poorly understood. Recent data have shown that sensory stimuli elicit activity in ensembles of cortical neurons that recapitulate stereotyped spontaneous activity patterns. Here, we elucidate a possible mechanism by which gating of patterned population cortical activity occurs. In this study, sensory-evoked all-or-none cortical population responses were observed in the mouse auditory cortex in vivo and similar stochastic cortical responses were observed in a colliculo-thalamocortical brain slice preparation. Cortical...
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